4-(Cbz-amino)-1-Boc-piperidine-4-carboxylic acid

4-(Cbz-amino)-1-Boc-piperidine-4-carboxylic acid - Names and Identifiers

Name	4-{[(benzyloxy)carbonyl]amino}-1-(tert-butoxycarbonyl)piperidine-4-carboxylic acid
Synonyms	Z-PIP(BOC)-OH Z-4-AMINO-1-BOC-PIPERIDINE-4-CARBOXYLIC ACID 1-BOC-4-N-CBZ-AMINOPIPERIDINE-4-CARBOXYLIC ACID 4-(Cbz-amino)-1-Boc-piperidine-4-carboxylic acid N-BOC-4-(N-CBZ-AMINO) PIPERIDINE-4-CARBOXYLIC ACID 1-N-BOC-4-N-CBZ-AMINO-PIPERIDINE-4-CARBOXYLIC ACID 4-(BENZYLOXYCARBONYLAMINO)-1-(TERT-BUTOXYCARBONYL)PIPERIDINE-4-CARBOXYLIC ACID 4-BENZYLOXYCARBONYLAMINO-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-TERT-BUTYL ESTER 4-Benzyloxycarbonylamino-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester 4-{[(benzyloxy)carbonyl]amino}-1-(tert-butoxycarbonyl)piperidine-4-carboxylic acid 4-{[(Benzyloxy)carbonyl]amino}-1-(tert-butoxycarbonyl)piperidine-4-carboxylic acid 1,4-Piperidinedicarboxylic acid, 4-[[(phenylmethoxy)carbonyl]amino]-, 1-(1,1-dimethylethyl) ester
CAS	288154-16-5
InChI	InChI=1/C19H26N2O6/c1-18(2,3)27-17(25)21-11-9-19(10-12-21,15(22)23)20-16(24)26-13-14-7-5-4-6-8-14/h4-8H,9-13H2,1-3H3,(H,20,24)(H,22,23)

4-(Cbz-amino)-1-Boc-piperidine-4-carboxylic acid - Physico-chemical Properties

Molecular Formula	C19H26N2O6
Molar Mass	378.42
Density	1.26±0.1 g/cm3(Predicted)
Boling Point	556.1±50.0 °C(Predicted)
Flash Point	290.1°C
Vapor Presure	3.35E-13mmHg at 25°C
pKa	3.84±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.567

4-(Cbz-amino)-1-Boc-piperidine-4-carboxylic acid - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
HS Code	29333990

4-(Cbz-amino)-1-Boc-piperidine-4-carboxylic acid - Introduction

4-{[(benzyloxy)carbonyl]amino}-1-(tert-butoxycarbonyl)piperidine-4-carboxylic acid is an organic compound with the chemical formula C23H30N2O6.

Its properties are as follows:
Appearance: White crystalline solid
Melting point: 78-80 ° C
Density: 1.19g/cm3
Solubility: Soluble in common organic solvents such as dimethyl sulfoxide and dichloromethane

4-{[(benzyloxy)carbonyl]amino}-1-(tert-butoxycarbonyl)piperidine-4-carboxylic acid is mainly used as an important intermediate in organic synthesis. It can be used to synthesize drugs, pesticides and biologically active compounds. Because of its very special chemical structure, it has wide application potential in drug research and development.

4-{[(benzyloxy)carbonyl]amino}-1-(tert-butoxycarbonyl)piperidine-4-carboxylic acid is generally prepared by reacting 4-benzyloxycarbonylaminopiperidine with tert-butyl chloroformate, followed by purification and crystallization to obtain the target product.

Regarding safety information, the toxicity and danger of this compound have not been reported and evaluated in detail. Appropriate laboratory safety measures should be taken when handling the compound, including wearing appropriate personal protective equipment (such as gloves and protective glasses) to avoid contact with skin and eyes. At the same time, ensure good ventilation during operation and avoid direct inhalation of volatiles of the compound. Due to the lack of detailed toxicity data, please evaluate and control the risk of this compound in specific applications.

Last Update：2024-04-09 21:11:58